Here's an idea if you're flying with a kid in a car seat, and you have connecting flights: try reserving seats on the opposite side of the airplane for each flight [i.e., put the car seat in A for one leg and F for the next.]
Chances are, you'll be torqued toward the car seat and its inhabitant for a good 75% of the flight. And if you have to sit like that, on the same side, for the entire trip, your back and neck will be screwed. up.
I'm sorry, did I say "your"? I meant "my."
[And your results may vary, of course, depending on your kids' temperament, but breaking up the cross-country flight seemed to work pretty well for the kid, who seemed happy for chances to stretch her legs and run along peoplemovers during connections. If you're doping them with the Benadryl, you're better off with non-stop. No fun running for a plane with a zonked out kid AND a car seat.]