I didn't check the Ono or O Bar side, but the two tiny bathrooms tucked into the alcove just past the check-in/concierge have sinks so small, you couldn't even do blow on them. Not the Hotel Gansevoort bathrooms I've heard about...
[update: if this knee-scraping description of Ono's any indication, the bathrooms sound more likely to have altars for vampires to drink infant blood than changing tables.]